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Download Molecular Basis of Pain Induction ePub

by John N. Wood

Download Molecular Basis of Pain Induction ePub
  • ISBN 0471346071
  • ISBN13 978-0471346074
  • Language English
  • Author John N. Wood
  • Publisher Wiley-Liss; 1 edition (January 21, 2000)
  • Pages 320
  • Formats txt doc azw txt
  • Category Medicine
  • Subcategory Medicine
  • Size ePub 1754 kb
  • Size Fb2 1286 kb
  • Rating: 4.8
  • Votes: 591

The scientific understanding of pain mechanisms has increaseddramatically in the last few years, and, in turn, so has the needfor a comprehensive volume on the molecular biology of pain and thedevelopment of analgesic drugs. Molecular Basis of Pain Inductionprovides a much-needed reference that covers a broad spectrum ofissues while focusing on the molecular aspects of pain and the mostrecent genetic studies.This volume reviews the numerous recent advances in the molecularaspects of pain that have aided in the development of analgesicdrugs. In such a rapidly growing area of biology, it is essentialto thoroughly comprehend how genes involved in pain are identifiedand whether any new drugs have resulted from pain studies. Thedevelopment and function of nociceptors is one of the outcomes ofthese vital molecular genetic studies, and this text reviews theactivation of nociceptors by a variety of chemical, thermal, andmechanical stimuli. Some of the other fascinating topics discussedin Molecular Basis of Pain Induction are:* Properties and advances in the study of pain-sensing sensoryneurons (nociceptors)* The use of mouse null mutants for the study of problems ingenetic background and behavioral research* Insights gained from genetic studies in worms and flies that haveaided in the understanding of human sensory neuron function* The detection of noxious mechanical damage* Bradykinin, which evokes pain, and opioid peptides, which blockpainContaining an abundance of useful illustrations and photos toaccompany this indispensable text, Molecular Basis of PainInduction is a resourceful guide for cell and molecular biologists,researchers in pharmaceutical companies, and neuroscientists alike.

Some of the other fascinating topics discussed in Molecular Basis of Pain Induction are . John Nicholas Wood FRS is a British neurobiologist, and Head of the Molecular Nociception Group, at University College London. Request permission to reuse content from this site.

Some of the other fascinating topics discussed in Molecular Basis of Pain Induction are . Genetic Approaches to Nociceptor Development (N. Abson, et a. Neurotrophic Factor Requirements of Developing Sensory Neurons (A. Davies). Neurotrophic Signaling and Sensory Neuron Survival and Function (I. Silos-Santiago).

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Start by marking Molecular Basis of Pain Induction as Want to Read: Want to Read savin. ant to Read. The scientific understanding of pain mechanisms has increased dramatically in the last few years, and, in turn, so has the need for a comprehensive volume on the molecular biology of pain and the development of analgesic drugs.

oceedings{Wood1999MolecularBO, title {Molecular Basis of Pain Induction}, author {John N Wood}, year . Molecular Approaches to the Study of Pain (R. Mannion, et a.

oceedings{Wood1999MolecularBO, title {Molecular Basis of Pain Induction}, author {John N Wood}, year {1999} }. John N Wood. Glial Cell Line-Derived Neurotrophic Factor and Nociceptive Neurons (S. McMahon & D. Bennett). Sensory Neuron-Specific Ion Channels and Receptors (A. Akopian, et a.

Cite this publication. stimulation by protons. We investigated the structural basis for protons and magnesium modulation of fully capsaicin-bound human receptors.

ISBN: 9780471346074; The scientific understanding of pain mechanisms has increased dramatically in the last few years, and, in turn, so has the need for a comprehensive volume on the molecular biology of pain and the development of analgesic drugs

ISBN: 9780471346074; The scientific understanding of pain mechanisms has increased dramatically in the last few years, and, in turn, so has the need for a comprehensive volume on the molecular biology of pain and the development of analgesic drugs. Molecular Basis of Pain Induction provides a much–needed reference that covers a broad spectrum of issues while focusing on the molecular aspects of pain and the most recent genetic studies.

Report site problems to: webmaster. Molecular Basis of Pain Induction. The twenty first century has seen a revolution in our understanding of the receptor systems and regulatory pathways that underlie the responses of these specialised cells to the occurrence of tissue damage. Pathobiology of visceral pain: molecular mechanisms and therapeutic implications.

The cell and molecular basis of mechanical, cold, and inflammatory pain. B Abrahamsen, J Zhao, CO Asante, CM Cendan, S Marsh

Articles Cited by. Title. An SCN9A channelopathy causes congenital inability to experience pain. The cell and molecular basis of mechanical, cold, and inflammatory pain. B Abrahamsen, J Zhao, CO Asante, CM Cendan, S Marsh,. Science 321 (5889), 702-705, 2008. Sensory neuron sodium channel Nav1. 8 is essential for pain at low temperatures. K Zimmermann, A Leffler, A Babes, CM Cendan, RW Carr, J Kobayashi

Pain behavior correlates well with central input from sensory neurons measured ly in vivo.

Molecular Nociception Group, University College London (UCL), Gower Street, London, WC1E 6BT, UK. Find this author on Google Scholar. Pain behavior correlates well with central input from sensory neurons measured ly in vivo. These data demonstrate that Na v . -expressing neurons are essential for mechanical, cold, and inflammatory pain but not for neuropathic pain or heat sensing.

Neurobiological Basis of MigrainePhilip R. Holland, Jan Hoffmann, and Peter J. Goadsby.

The Measurement of Pain in the Laboratory RodentJeffrey S. Mogil. Invertebrate Models of Nociception: Learning from Flies and WormsDaniel Hesselson, Denise S. Walker, Joshua Neil Massingham, William R. Schafer, G. Gregory Neely, and Yee Lian Chew. Neurobiological Basis of MigrainePhilip R. Effect of Sleep Loss on PainChloe Alexandre, Alban Latremoliere, and Patrick H. Finan.

Molecular mechanisms of nociception. The anatomic basis of vertebrogenic pain and the autonomic syndrome associated with lumbar disk extrusion. Nature 2001;413:203–210. Am J Roentgenol 1989;152:1277–1289. Contemporary Pain Medicine (Integrative Pain Medicine: The Science and Practice of Complementary and Alternative Medicine in Pain Management).