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Download Benzodiazepines: A Handbook. Basic Data, Analytical Methods, Pharmacokinetics and Comprehensive Literature ePub

by H. Schütz

Download Benzodiazepines: A Handbook. Basic Data, Analytical Methods, Pharmacokinetics and Comprehensive Literature ePub
  • ISBN 3540112707
  • ISBN13 978-3540112709
  • Language English
  • Author H. Schütz
  • Publisher Springer; 1 edition (April 28, 1982)
  • Pages 439
  • Formats mobi doc docx lrf
  • Category Medicine
  • Subcategory Medicine
  • Size ePub 1529 kb
  • Size Fb2 1788 kb
  • Rating: 4.1
  • Votes: 285

To comment at length on the importance of the benzodiazepines seems superfluous within the scope of this preface. No other class of active substances has experienced an even approximately compa­ rable advance in the past two decades. It is therefore not surprising that the formerly dominant barbiturates and bromocarbamides have had to give way in many fields to the benzodiazepines, which now rank first (Proudfoot and Park [1828]). Closely linked with the great therapeutic importance of the benzodia­ zepines are analytical problems. Detection and the determination of blood levels can be necessary under therapeutic aspects, for instance in working out optimally effective levels in the treatment of epileptic conditions ("drug monitoring"), but also in connection with questions at issue in toxicology and traffic medicine. A toxicological analysis can be subdivided into the following steps: Detection (identification including screening) Determination (e. g. blood, plasma or serum levels) Interpretation of the analytical results. This book is intended as a contribution to each of these chapters: The part "Analytical Data" (pp.I-122) gives a comprehensive collec­ tion of data, e.g. general and chromatographic data (TLC, GLC) as well as spectra (UV, IR, MS) of 19 commercial preparations, 23 important metabolites and 18 hydrolysis derivatives. Information about biotransformation and the possible formation of aminobenzo­ phenone derivatives is also given. The most important analytical methods are presented in an extensive review on pp.123-204 in order to make it possible to select the optimum method on the basis of the essential data.

Basic Data, Analytical Methods, Pharmacokinetics and Comprehensive Literature.

Show all. Table of contents (14 chapters). Formula Index and Melting Points. Pages 1-3. Schütz, D. er. Index of Treated Substances. Basic Data, Analytical Methods, Pharmacokinetics and Comprehensive Literature.

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Benzodiazepines II contains a complete update of information, with new .

Benzodiazepines II contains a complete update of information, with new substances as well as new methods of analysis and pharmacokinetics. A comprehensive list of more than 7500 references is a special feature which makes the volume a practical guide for the non-analyst as well. Benzodiazepines II: a handbook : basic data, analytical methods, pharmacokinetics and comprehensive literature, Том 2.

Basic Data, Analytical Methods, Pharmacokinetics and Comprehensive Literature . Coauthors & Alternates.

Basic Data, Analytical Methods, Pharmacokinetics and Comprehensive Literature: Benzodiazepines: A Handbook. Basic Data, Analytical Methods, Pharmacokinetics and Comprehensive Literature: ISBN 9783540112709 (978-3-540-1127) Hardcover, Springer, 1982. Benzodiazepines: A Handbook.

This book is intended as a contribution to each of these chapters: The part "Analytical Data" (p. -122) gives a comprehensive collec tion of data, . general and chromatographic data (TLC, GLC) as well as spectra (UV, IR, MS) of 19 commercial preparations, 23 important metabolites and 18 hydrolysis derivatives. Information about biotransformation and the possible formation of aminobenzo phenone derivatives is also given.

Benzodiazepines, a Handbook; Basic Data, Analytical Methods, Pharmakokinetics and Comprehensive Literature. Springer-Verlag, Heidelberg 1982, 439 . DM 198,– Daniela Linden. Profile of acute tolerance to three sedative anxiolytics. Everett H. Ellinwood, Markku Linnoila, Martha E. Easler, David W. Molter.

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